array(4) {
  ["posts_per_page"]=>
  string(1) "5"
  ["cat"]=>
  int(21)
  ["p"]=>
  string(0) ""
  ["suppress_filters"]=>
  int(0)
}
array(6) {
  ["posts_per_page"]=>
  string(1) "5"
  ["cat"]=>
  int(21)
  ["p"]=>
  string(0) ""
  ["suppress_filters"]=>
  int(0)
  ["paged"]=>
  int(13)
  ["meta_query"]=>
  array(1) {
    [0]=>
    array(0) {
    }
  }
}
object(WP_Query)#3378 (56) {
  ["query"]=>
  array(6) {
    ["posts_per_page"]=>
    string(1) "5"
    ["cat"]=>
    int(21)
    ["p"]=>
    string(0) ""
    ["suppress_filters"]=>
    int(0)
    ["paged"]=>
    int(13)
    ["meta_query"]=>
    array(1) {
      [0]=>
      array(0) {
      }
    }
  }
  ["query_vars"]=>
  array(62) {
    ["posts_per_page"]=>
    int(5)
    ["cat"]=>
    int(21)
    ["p"]=>
    int(0)
    ["suppress_filters"]=>
    int(0)
    ["paged"]=>
    int(13)
    ["meta_query"]=>
    array(1) {
      [0]=>
      array(0) {
      }
    }
    ["error"]=>
    string(0) ""
    ["m"]=>
    string(0) ""
    ["post_parent"]=>
    string(0) ""
    ["subpost"]=>
    string(0) ""
    ["subpost_id"]=>
    string(0) ""
    ["attachment"]=>
    string(0) ""
    ["attachment_id"]=>
    int(0)
    ["name"]=>
    string(0) ""
    ["static"]=>
    string(0) ""
    ["pagename"]=>
    string(0) ""
    ["page_id"]=>
    int(0)
    ["second"]=>
    string(0) ""
    ["minute"]=>
    string(0) ""
    ["hour"]=>
    string(0) ""
    ["day"]=>
    int(0)
    ["monthnum"]=>
    int(0)
    ["year"]=>
    int(0)
    ["w"]=>
    int(0)
    ["category_name"]=>
    string(12) "publications"
    ["tag"]=>
    string(0) ""
    ["tag_id"]=>
    string(0) ""
    ["author"]=>
    string(0) ""
    ["author_name"]=>
    string(0) ""
    ["feed"]=>
    string(0) ""
    ["tb"]=>
    string(0) ""
    ["comments_popup"]=>
    string(0) ""
    ["meta_key"]=>
    string(0) ""
    ["meta_value"]=>
    string(0) ""
    ["preview"]=>
    string(0) ""
    ["s"]=>
    string(0) ""
    ["sentence"]=>
    string(0) ""
    ["fields"]=>
    string(0) ""
    ["menu_order"]=>
    string(0) ""
    ["category__in"]=>
    array(0) {
    }
    ["category__not_in"]=>
    array(0) {
    }
    ["category__and"]=>
    array(0) {
    }
    ["post__in"]=>
    array(0) {
    }
    ["post__not_in"]=>
    array(0) {
    }
    ["tag__in"]=>
    array(0) {
    }
    ["tag__not_in"]=>
    array(0) {
    }
    ["tag__and"]=>
    array(0) {
    }
    ["tag_slug__in"]=>
    array(0) {
    }
    ["tag_slug__and"]=>
    array(0) {
    }
    ["post_parent__in"]=>
    array(0) {
    }
    ["post_parent__not_in"]=>
    array(0) {
    }
    ["author__in"]=>
    array(0) {
    }
    ["author__not_in"]=>
    array(0) {
    }
    ["ignore_sticky_posts"]=>
    bool(false)
    ["cache_results"]=>
    bool(true)
    ["update_post_term_cache"]=>
    bool(true)
    ["update_post_meta_cache"]=>
    bool(true)
    ["post_type"]=>
    string(0) ""
    ["nopaging"]=>
    bool(false)
    ["comments_per_page"]=>
    string(2) "50"
    ["no_found_rows"]=>
    bool(false)
    ["order"]=>
    string(4) "DESC"
  }
  ["tax_query"]=>
  object(WP_Tax_Query)#3399 (6) {
    ["queries"]=>
    array(1) {
      [0]=>
      array(5) {
        ["taxonomy"]=>
        string(8) "category"
        ["terms"]=>
        array(1) {
          [0]=>
          int(21)
        }
        ["field"]=>
        string(7) "term_id"
        ["operator"]=>
        string(2) "IN"
        ["include_children"]=>
        bool(true)
      }
    }
    ["relation"]=>
    string(3) "AND"
    ["table_aliases":protected]=>
    array(1) {
      [0]=>
      string(21) "wp_term_relationships"
    }
    ["queried_terms"]=>
    array(1) {
      ["category"]=>
      array(2) {
        ["terms"]=>
        array(1) {
          [0]=>
          int(21)
        }
        ["field"]=>
        string(7) "term_id"
      }
    }
    ["primary_table"]=>
    string(8) "wp_posts"
    ["primary_id_column"]=>
    string(2) "ID"
  }
  ["meta_query"]=>
  object(WP_Meta_Query)#3398 (9) {
    ["queries"]=>
    array(0) {
    }
    ["relation"]=>
    string(3) "AND"
    ["meta_table"]=>
    NULL
    ["meta_id_column"]=>
    NULL
    ["primary_table"]=>
    NULL
    ["primary_id_column"]=>
    NULL
    ["table_aliases":protected]=>
    array(0) {
    }
    ["clauses":protected]=>
    array(0) {
    }
    ["has_or_relation":protected]=>
    bool(false)
  }
  ["date_query"]=>
  bool(false)
  ["post_count"]=>
  int(5)
  ["current_post"]=>
  int(-1)
  ["in_the_loop"]=>
  bool(false)
  ["comment_count"]=>
  int(0)
  ["current_comment"]=>
  int(-1)
  ["found_posts"]=>
  string(2) "67"
  ["max_num_pages"]=>
  float(14)
  ["max_num_comment_pages"]=>
  int(0)
  ["is_single"]=>
  bool(false)
  ["is_preview"]=>
  bool(false)
  ["is_page"]=>
  bool(false)
  ["is_archive"]=>
  bool(true)
  ["is_date"]=>
  bool(false)
  ["is_year"]=>
  bool(false)
  ["is_month"]=>
  bool(false)
  ["is_day"]=>
  bool(false)
  ["is_time"]=>
  bool(false)
  ["is_author"]=>
  bool(false)
  ["is_category"]=>
  bool(true)
  ["is_tag"]=>
  bool(false)
  ["is_tax"]=>
  bool(false)
  ["is_search"]=>
  bool(false)
  ["is_feed"]=>
  bool(false)
  ["is_comment_feed"]=>
  bool(false)
  ["is_trackback"]=>
  bool(false)
  ["is_home"]=>
  bool(false)
  ["is_404"]=>
  bool(false)
  ["is_comments_popup"]=>
  bool(false)
  ["is_paged"]=>
  bool(true)
  ["is_admin"]=>
  bool(false)
  ["is_attachment"]=>
  bool(false)
  ["is_singular"]=>
  bool(false)
  ["is_robots"]=>
  bool(false)
  ["is_posts_page"]=>
  bool(false)
  ["is_post_type_archive"]=>
  bool(false)
  ["query_vars_hash":"WP_Query":private]=>
  string(32) "6cdbe0a4e4d83400a5f4c996de6e126b"
  ["query_vars_changed":"WP_Query":private]=>
  bool(false)
  ["thumbnails_cached"]=>
  bool(false)
  ["stopwords":"WP_Query":private]=>
  NULL
  ["compat_fields":"WP_Query":private]=>
  array(2) {
    [0]=>
    string(15) "query_vars_hash"
    [1]=>
    string(18) "query_vars_changed"
  }
  ["compat_methods":"WP_Query":private]=>
  array(2) {
    [0]=>
    string(16) "init_query_flags"
    [1]=>
    string(15) "parse_tax_query"
  }
  ["tribe_is_event"]=>
  bool(false)
  ["tribe_is_multi_posttype"]=>
  bool(false)
  ["tribe_is_event_category"]=>
  bool(false)
  ["tribe_is_event_venue"]=>
  bool(false)
  ["tribe_is_event_organizer"]=>
  bool(false)
  ["tribe_is_event_query"]=>
  bool(false)
  ["tribe_is_past"]=>
  bool(false)
  ["request"]=>
  string(920) "SELECT SQL_CALC_FOUND_ROWS  wp_posts.ID FROM wp_posts  INNER JOIN wp_term_relationships ON (wp_posts.ID = wp_term_relationships.object_id) JOIN wp_icl_translations t
							ON wp_posts.ID = t.element_id
								AND t.element_type = CONCAT('post_', wp_posts.post_type)  WHERE 1=1  AND ( 
  wp_term_relationships.term_taxonomy_id IN (21)
) AND wp_posts.post_type = 'post' AND (wp_posts.post_status = 'publish' OR wp_posts.post_status = 'tribe-ea-success' OR wp_posts.post_status = 'tribe-ea-failed' OR wp_posts.post_status = 'tribe-ea-schedule' OR wp_posts.post_status = 'tribe-ea-pending' OR wp_posts.post_status = 'tribe-ea-draft') AND ( ( t.language_code = 'en' AND wp_posts.post_type  IN ('post','page','tribe_venue','tribe_organizer','tribe_events' )  ) OR wp_posts.post_type  NOT  IN ('post','page','tribe_venue','tribe_organizer','tribe_events' )  ) GROUP BY wp_posts.ID ORDER BY wp_posts.post_date DESC LIMIT 60, 5"
  ["posts"]=>
  array(5) {
    [0]=>
    object(WP_Post)#4767 (24) {
      ["ID"]=>
      int(6086)
      ["post_author"]=>
      string(1) "7"
      ["post_date"]=>
      string(19) "2011-04-05 17:29:01"
      ["post_date_gmt"]=>
      string(19) "2011-04-05 16:29:01"
      ["post_content"]=>
      string(0) ""
      ["post_title"]=>
      string(211) "Trabectedin plus pegylated liposomal doxorubicin in relapsed ovarian cancer: outcomes in the partially platinum-sensitive (platinum-free interval 6¿12 months) subpopulation of OVA-301 phase III randomized trial"
      ["post_excerpt"]=>
      string(0) ""
      ["post_status"]=>
      string(7) "publish"
      ["comment_status"]=>
      string(6) "closed"
      ["ping_status"]=>
      string(6) "closed"
      ["post_password"]=>
      string(0) ""
      ["post_name"]=>
      string(191) "trabectedin-plus-pegylated-liposomal-doxorubicin-in-relapsed-ovarian-cancer-outcomes-in-the-partially-platinum-sensitive-platinum-free-interval-612-months-subpopulation-of-ova-301-phase-iii-r"
      ["to_ping"]=>
      string(0) ""
      ["pinged"]=>
      string(0) ""
      ["post_modified"]=>
      string(19) "2017-01-03 12:35:40"
      ["post_modified_gmt"]=>
      string(19) "2017-01-03 11:35:40"
      ["post_content_filtered"]=>
      string(0) ""
      ["post_parent"]=>
      int(0)
      ["guid"]=>
      string(32) "http://www.pharmamar.com/?p=6086"
      ["menu_order"]=>
      int(0)
      ["post_type"]=>
      string(4) "post"
      ["post_mime_type"]=>
      string(0) ""
      ["comment_count"]=>
      string(1) "0"
      ["filter"]=>
      string(3) "raw"
    }
    [1]=>
    object(WP_Post)#3422 (24) {
      ["ID"]=>
      int(6140)
      ["post_author"]=>
      string(1) "7"
      ["post_date"]=>
      string(19) "2010-04-06 12:39:49"
      ["post_date_gmt"]=>
      string(19) "2010-04-06 11:39:49"
      ["post_content"]=>
      string(0) ""
      ["post_title"]=>
      string(100) "PM01183, a new DNA minor-groove covalent binder with potent in vitro and in vivo antitumour activity"
      ["post_excerpt"]=>
      string(0) ""
      ["post_status"]=>
      string(7) "publish"
      ["comment_status"]=>
      string(6) "closed"
      ["ping_status"]=>
      string(6) "closed"
      ["post_password"]=>
      string(0) ""
      ["post_name"]=>
      string(99) "pm01183-a-new-dna-minor-groove-covalent-binder-with-potent-in-vitro-and-in-vivo-antitumour-activity"
      ["to_ping"]=>
      string(0) ""
      ["pinged"]=>
      string(0) ""
      ["post_modified"]=>
      string(19) "2017-01-03 12:36:05"
      ["post_modified_gmt"]=>
      string(19) "2017-01-03 11:36:05"
      ["post_content_filtered"]=>
      string(0) ""
      ["post_parent"]=>
      int(0)
      ["guid"]=>
      string(32) "http://www.pharmamar.com/?p=6140"
      ["menu_order"]=>
      int(0)
      ["post_type"]=>
      string(4) "post"
      ["post_mime_type"]=>
      string(0) ""
      ["comment_count"]=>
      string(1) "0"
      ["filter"]=>
      string(3) "raw"
    }
    [2]=>
    object(WP_Post)#3421 (24) {
      ["ID"]=>
      int(6070)
      ["post_author"]=>
      string(1) "7"
      ["post_date"]=>
      string(19) "2010-04-05 17:13:59"
      ["post_date_gmt"]=>
      string(19) "2010-04-05 16:13:59"
      ["post_content"]=>
      string(0) ""
      ["post_title"]=>
      string(76) "Trabectedin Plus Pegylated Liposomal Doxorubicin in Recurrent Ovarian Cancer"
      ["post_excerpt"]=>
      string(0) ""
      ["post_status"]=>
      string(7) "publish"
      ["comment_status"]=>
      string(6) "closed"
      ["ping_status"]=>
      string(6) "closed"
      ["post_password"]=>
      string(0) ""
      ["post_name"]=>
      string(76) "trabectedin-plus-pegylated-liposomal-doxorubicin-in-recurrent-ovarian-cancer"
      ["to_ping"]=>
      string(0) ""
      ["pinged"]=>
      string(0) ""
      ["post_modified"]=>
      string(19) "2017-01-03 12:36:31"
      ["post_modified_gmt"]=>
      string(19) "2017-01-03 11:36:31"
      ["post_content_filtered"]=>
      string(0) ""
      ["post_parent"]=>
      int(0)
      ["guid"]=>
      string(32) "http://www.pharmamar.com/?p=6070"
      ["menu_order"]=>
      int(0)
      ["post_type"]=>
      string(4) "post"
      ["post_mime_type"]=>
      string(0) ""
      ["comment_count"]=>
      string(1) "0"
      ["filter"]=>
      string(3) "raw"
    }
    [3]=>
    object(WP_Post)#3402 (24) {
      ["ID"]=>
      int(6149)
      ["post_author"]=>
      string(1) "7"
      ["post_date"]=>
      string(19) "2009-04-06 12:58:45"
      ["post_date_gmt"]=>
      string(19) "2009-04-06 11:58:45"
      ["post_content"]=>
      string(0) ""
      ["post_title"]=>
      string(39) "The mechanism of action of plitidepsin."
      ["post_excerpt"]=>
      string(0) ""
      ["post_status"]=>
      string(7) "publish"
      ["comment_status"]=>
      string(6) "closed"
      ["ping_status"]=>
      string(6) "closed"
      ["post_password"]=>
      string(0) ""
      ["post_name"]=>
      string(38) "the-mechanism-of-action-of-plitidepsin"
      ["to_ping"]=>
      string(0) ""
      ["pinged"]=>
      string(0) ""
      ["post_modified"]=>
      string(19) "2016-04-06 13:00:17"
      ["post_modified_gmt"]=>
      string(19) "2016-04-06 12:00:17"
      ["post_content_filtered"]=>
      string(0) ""
      ["post_parent"]=>
      int(0)
      ["guid"]=>
      string(32) "http://www.pharmamar.com/?p=6149"
      ["menu_order"]=>
      int(0)
      ["post_type"]=>
      string(4) "post"
      ["post_mime_type"]=>
      string(0) ""
      ["comment_count"]=>
      string(1) "0"
      ["filter"]=>
      string(3) "raw"
    }
    [4]=>
    object(WP_Post)#3403 (24) {
      ["ID"]=>
      int(6100)
      ["post_author"]=>
      string(1) "7"
      ["post_date"]=>
      string(19) "2009-04-06 09:37:43"
      ["post_date_gmt"]=>
      string(19) "2009-04-06 08:37:43"
      ["post_content"]=>
      string(0) ""
      ["post_title"]=>
      string(224) "Efficacy and Safety of Trabectedin in Patients With Advanced or Metastatic Liposarcoma or Leiomyosarcoma After Failure of Prior Anthracyclines and Ifosfamide: Results of a Randomized Phase II Study of Two Different Schedules"
      ["post_excerpt"]=>
      string(0) ""
      ["post_status"]=>
      string(7) "publish"
      ["comment_status"]=>
      string(6) "closed"
      ["ping_status"]=>
      string(6) "closed"
      ["post_password"]=>
      string(0) ""
      ["post_name"]=>
      string(199) "efficacy-and-safety-of-trabectedin-in-patients-with-advanced-or-metastatic-liposarcoma-or-leiomyosarcoma-after-failure-of-prior-anthracyclines-and-ifosfamide-results-of-a-randomized-phase-ii-study-of"
      ["to_ping"]=>
      string(0) ""
      ["pinged"]=>
      string(0) ""
      ["post_modified"]=>
      string(19) "2017-01-03 12:38:12"
      ["post_modified_gmt"]=>
      string(19) "2017-01-03 11:38:12"
      ["post_content_filtered"]=>
      string(0) ""
      ["post_parent"]=>
      int(0)
      ["guid"]=>
      string(32) "http://www.pharmamar.com/?p=6100"
      ["menu_order"]=>
      int(0)
      ["post_type"]=>
      string(4) "post"
      ["post_mime_type"]=>
      string(0) ""
      ["comment_count"]=>
      string(1) "0"
      ["filter"]=>
      string(3) "raw"
    }
  }
  ["post"]=>
  object(WP_Post)#4767 (24) {
    ["ID"]=>
    int(6086)
    ["post_author"]=>
    string(1) "7"
    ["post_date"]=>
    string(19) "2011-04-05 17:29:01"
    ["post_date_gmt"]=>
    string(19) "2011-04-05 16:29:01"
    ["post_content"]=>
    string(0) ""
    ["post_title"]=>
    string(211) "Trabectedin plus pegylated liposomal doxorubicin in relapsed ovarian cancer: outcomes in the partially platinum-sensitive (platinum-free interval 6¿12 months) subpopulation of OVA-301 phase III randomized trial"
    ["post_excerpt"]=>
    string(0) ""
    ["post_status"]=>
    string(7) "publish"
    ["comment_status"]=>
    string(6) "closed"
    ["ping_status"]=>
    string(6) "closed"
    ["post_password"]=>
    string(0) ""
    ["post_name"]=>
    string(191) "trabectedin-plus-pegylated-liposomal-doxorubicin-in-relapsed-ovarian-cancer-outcomes-in-the-partially-platinum-sensitive-platinum-free-interval-612-months-subpopulation-of-ova-301-phase-iii-r"
    ["to_ping"]=>
    string(0) ""
    ["pinged"]=>
    string(0) ""
    ["post_modified"]=>
    string(19) "2017-01-03 12:35:40"
    ["post_modified_gmt"]=>
    string(19) "2017-01-03 11:35:40"
    ["post_content_filtered"]=>
    string(0) ""
    ["post_parent"]=>
    int(0)
    ["guid"]=>
    string(32) "http://www.pharmamar.com/?p=6086"
    ["menu_order"]=>
    int(0)
    ["post_type"]=>
    string(4) "post"
    ["post_mime_type"]=>
    string(0) ""
    ["comment_count"]=>
    string(1) "0"
    ["filter"]=>
    string(3) "raw"
  }
}

Publication: Ann Oncol

Year: 2011

Trabectedin plus pegylated liposomal doxorubicin in relapsed ovarian cancer: outcomes in the partially platinum-sensitive (platinum-free interval 6¿12 months) subpopulation of OVA-301 phase III randomized trial

Authors:
Poveda, A.; Vergote, I.; Tjulandin, S.; Kong, B.; Roy, M.; Chan, S.; Filipczyk-Cisarz, E.; Hagberg, H.; Kaye, S.B.; Colombo, N.; Lebedinsky, C.; Parekh, T.; Gomez, J.; Park, Y.C.; Alfaro, V.; Monk, B.J.

Publication: Br J Pharmacol

Year: 2010

PM01183, a new DNA minor-groove covalent binder with potent in vitro and in vivo antitumour activity

Authors:
Leal, J.F.M.; Martínez-Díez, M.; García-Hernández, V.; Moneo, V.; Domingo, A.; Bueren-Calabuig, J.A.; Negri, A.; Gago, F.; Guillén-Navarro, M.J.; Avilés, P.; Cuevas, C.; García-Fernández, L.F.; Galmarini, C.M.

Publication: J Clin Oncol

Year: 2010

Trabectedin Plus Pegylated Liposomal Doxorubicin in Recurrent Ovarian Cancer

Authors:
Monk, B.J.; Herzog, T.J.; Kaye, S.B.; Krasner, C.N.; Vermorken, J.B.; Muggia, F.M.; Pujade-Lauraine, E.; Lisyanskaya, A.S.; Makhson, A.N.; Rolski, J.; Gorbounova, V.A.; Ghatage, P.; Bidzinski, M.; Shen, K.; Nganv, H.Y-S.; Vergote, I.B.; Nam, J-H.; Park, Y.C.; Lebedinsky, C.A.; Poveda, A.M.

Publication: Curr Opin Investig Drugs

Year: 2009

The mechanism of action of plitidepsin.

Authors:
Muñoz-Alonso, M.J.; González-Santiago, L.; Martínez, T.; Losada, A.; Galmarini, C.M.; Muñoz, A.

Publication: J Clin Oncol

Year: 2009

Efficacy and Safety of Trabectedin in Patients With Advanced or Metastatic Liposarcoma or Leiomyosarcoma After Failure of Prior Anthracyclines and Ifosfamide: Results of a Randomized Phase II Study of Two Different Schedules

Authors:
Demetri, G.D.; Chawla, S.P.; von Mehren, M.; Ritch, P.; Baker, L.H.; Blay, J.Y.; Hande, K.R.; Keohan, M.L.; Samuels, B.L.; Schuetze, S.; Lebedinsky, C.; Elsayed, Y.A.; Izquierdo, M.A.; Gómez, J.; Park, Y.C.; Le Cesne, A.

Oncology pipeline

PharmaMar develops and commercializes YONDELIS® in Europe and has three clinical-stage drug candidates under development for several types of solid and hematological cancers, Aplidin ®, Lurbinectedin, and PM184.

Science & Innovation

Our strong commitment to oncology translational research along with our deep understanding of the marine biodiversity of our oceans is placing us at the head of marine biotechnology.

Newsroom

If you need information about the company, our clinical trials, corporate images or multimedia, visit our newsroom